{"id":96,"date":"2020-12-12T13:42:05","date_gmt":"2020-12-12T13:42:05","guid":{"rendered":"http:\/\/newsofbharath.com\/?p=96"},"modified":"2020-12-12T13:42:05","modified_gmt":"2020-12-12T13:42:05","slug":"history-of-coronavirus","status":"publish","type":"post","link":"https:\/\/newsofbharath.com\/?p=96","title":{"rendered":"History of Coronavirus"},"content":{"rendered":"\n

Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds<\/p>\n\n\n\n

In humans these viruses cause respiratory tract infections<\/p>\n\n\n\n

Mild \u2013 common cold<\/p>\n\n\n\n

Lethal \u2013 SARS \u2013 Severe Acute Respiratory Syndrome<\/p>\n\n\n\n

MERS- Middle East Respiratory Syndrome<\/p>\n\n\n\n

COVID-19 \u2013 Coronavirus Disease 2019<\/p>\n\n\n\n

COVID-19 First identified in December 2019 in Wuhan.<\/p>\n\n\n\n

Coronaviuses were first discovered in 1930s<\/p>\n\n\n\n

Human coronaviruses discovered in 1960s<\/p>\n\n\n\n

MRCA- Most Recent Common Ancestor of all coronaviruses existed 8000 BCE, some as 55 million years or more, showing long term co-evolution with bat and avian species.<\/p>\n\n\n\n

\u03b1 coronavirus -2400 BCE<\/p>\n\n\n\n

\u03b2 coronavirus \u2013 3300 BCE<\/p>\n\n\n\n

\u01b3 coronavirus \u2013 2800 BCE<\/p>\n\n\n\n

\u018f coronavirus \u2013 3000 BCE<\/p>\n\n\n\n

Natural reservoir for coronavirus gene pool are<\/p>\n\n\n\n

\u03b2,\u03b1- coronaviruses in Bats<\/p>\n\n\n\n

\u01b3,\u018f \u2013 coronaviruses in Birds<\/p>\n\n\n\n

Human coronaviruses like 229E ~ Ghana Grp1 Bt Cov 1686 and 800 CE<\/p>\n\n\n\n

SARS related COV co-evoluted in Bats for a long time<\/p>\n\n\n\n

Ancestors of SARS-COV first infected genus Hipposideridac (Leaf nose Bats) then spread to Rhinolophidae (Horse shoe Bats) then to Para docxurus ( Asian palm civet) and finally to humans.<\/p>\n\n\n\n

In 2003, HCOV,SARS-COV has unique pathogenesis of both upper and lower respiratory tract infections.<\/p>\n\n\n\n

Mild symptoms producing COV<\/p>\n\n\n\n

  1. HCOV-OC43- Human coronavirus OC43 \u03b2-COV<\/li>
  2. HCOV-HKU1- Human coronavirus HKU1  \u03b2-COV<\/li>
  3. HCOV-229E- Human coronavirus 229E \u03b1-COV<\/li>
  4. HCOV-NL63- Human coronavirus NL63 \u03b1-COV<\/li><\/ol>\n\n\n\n

    Severe symptoms producing COV<\/p>\n\n\n\n

    1. Middle east respiratory syndrome related coronavirus-MERS-COV, \u03b2-COV<\/li>
    2. Severe acute respiratory syndrome coronavirus- SARS-COV, \u03b2-COV<\/li>
    3. Severe acute respiratory syndrome coronavirus 2- SARS-COV-2, \u03b2-COV<\/li><\/ol>\n\n\n\n

      So SARS-COV-2 \u03b2-COV has started infecting humans and has of now more than 11,924,855 cases and 545,332 deaths has occurred world wide.<\/p>\n","protected":false},"excerpt":{"rendered":"

      Coronaviruses are a group of related RNA viruses that cause diseases in mammals and birds In humans these viruses cause respiratory tract infections Mild \u2013 common cold Lethal \u2013 SARS \u2013 Severe Acute Respiratory Syndrome MERS- Middle East Respiratory Syndrome COVID-19 \u2013 Coronavirus Disease 2019 COVID-19 First identified in December 2019 in Wuhan. Coronaviuses were […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[3],"tags":[147,144,148,145,150,138,30,137,142,143,146,141,54,14,149,140],"class_list":["post-96","post","type-post","status-publish","format-standard","hentry","category-covid-19-updates","tag-alpha","tag-bats","tag-beta","tag-birds","tag-coevolution","tag-coronavirus","tag-covid-19-2","tag-history","tag-infection","tag-mers","tag-mrca","tag-respirstory","tag-rna","tag-sars","tag-strains","tag-viruses"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t